Reverse transcriptase (RT) inhibitors



Reverse transcriptase (RT) inhibitors
help block an important step in the HIV life cycle. There are two types of RT inhibitors.

Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) stall reproduction of HIV. They force the virus to use faulty versions of building blocks..



The FDA has approved these NRTIs:

Brand NameGeneric NameAbbreviation
Combivirzidovudine + lamivudineAZT + 3TC
EmtrivaemtricitabineFTC
Epivirlamivudine3TC
EpzicomAbacavir + lamivudineABC + 3TC
HividzalcitabineddC
RetrovirzidovudineAZT or ZDV
Stribildtenofovir + emtricitabine + elvitegravirTDF + FTC + EVG
Trizivirabacavir + zidovudine + lamivudineABC + AZT + 3TC
Truvadatenofovir DF + emtricitabineTDF + FTC
Videxdidanosine: buffered versionsddl
Videx ECdidanosine: delayed-release capsulesddl
Vireadtenofovir disoproxil fumarate (DF)TDF or Bis (POC) PMPA
Zeritstavudined4T
ZiagenabacavirABC














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