Paracetamol
Generic Name: paracetamol (oral/rectal) (par RA cet a MOL)
Alternate Name: acetaminophen (a SEET a MIN oh fen)
Alternate Name: acetaminophen (a SEET a MIN oh fen)
Paracetamol (acetaminophen) is a pain reliever and a fever reducer. The exact mechanism of action of is not known.
Paracetamol is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.
Paracetamol may also be used for other purposes not listed in this medication guide.
Important information
There are many brands and forms of paracetamol available and not all brands are listed on this leaflet.
Do not use more of this medication than is recommended. An overdose of paracetamol can cause serious harm. The maximum amount of paracetamol for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more paracetamol could cause damage to your liver. If you drink more than three alcoholic beverages per day, talk to your doctor before taking paracetamol and never use more than 2 grams (2000 mg) per day.
Do not use this medication without first talking to your doctor if you drink more than three alcoholic beverages per day or if you have had alcoholic liver disease (cirrhosis). You may not be able to use paracetamol .
Before using paracetamol , tell your doctor if you have liver disease or a history of alcoholism.
Do not use any other over-the-counter cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. Paracetamol is contained in many combination medicines. If you use certain products together you may accidentally use too much paracetamol . Read the label of any other medicine you are using to see if it contains paracetamol, acetaminophen or APAP. Avoid drinking alcohol while taking this medication. Alcohol may increase your risk of liver damage while taking paracetamol .
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate: Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Minor: Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan...
For the Consumer
Applies to acetaminophen: capsule, capsule liquid filled, elixir, liquid, powder, powder for solution, solution, suppository, suspension, syrup, tablet, tablet chewable, tablet disintegrating, tablet effervescent, tablet extended release.
As well as its needed effects, acetaminophen (the active ingredient contained in Paracetamol) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking acetaminophen, check with your doctor immediately:
Rare
If any of the following symptoms of overdose occur while taking acetaminophen, get emergency help immediately:
Symptoms of overdose:
Usual Adult Dose for Fever
Parental:
Weight 50 kg or greater: 1000 mg IV every 6 hours OR 650 mg IV every 4 hours Maximum Single Dose: 1000 mg Minimum Dosing Interval: every 4 hours Maximum Dose: 4000 mg per 24 hours Weight less than 50 kg: 15 mg/kg IV every 6 hours OR 12.5 mg/kg IV every 4 hours Maximum Single Dose: 15 mg/kg Minimum Dosing Interval: every 4 hours Maximum Dose: 75 mg/kg per 24 hours Oral: Immediate-release: 325 mg to 1 g orally every 4 to 6 hours Minimum Dosing Interval: every 4 hours Maximum Single Dose: 1000 mg Maximum Dose: 4 g per 24 hours.
Extended-Release: 1300 mg orally every 8 hours
Maximum dose: 3900 mg per 24 hours Rectal: 650 mg rectally every 4 to 6 hours Maximum dose: 3900 mg per 24 hours References
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Not all side effects for acetaminophen may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
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